Revision Date: January 20, 2015. : 93-58-3 . Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. The incidence of gastrointestinal adverse reactions, including diarrhea and loose stools, in the pediatric patients receiving the suspension, was comparable to the incidence seen in adult patients receiving tablets. Slightly soluble in water. g Allow the ice to melt and filter under suction. Temperature:23.0C. Methyl benzoate is a volatile aromatic ester compound widely used in perfumery industries. Above 83C use a closed system and ventilation. It is an ester with the chemical formula C6H5CO2CH3. Wash . Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. ; Methods and materials for containment and cleaning up: Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations. H302. 5. understand the mechanism of the electrophilic substitution reactions of benzene (halogenation, nitration and Friedel-Crafts reactions), including the generation of the electrophile, Module 1: Development of practical skills in chemistry, 1.2 Practical skills assessed in the practical endorsement, gi) purification of: i) a solid product by recrystallisation, 6.2 Nitrogen compounds, polymers and synthesis, a) the techniques and procedures used for the preparation and purification of organic solids involving use of a range of techniques including: ii) purification of an organic solid: filtration under reduced pressure; recrystallisation; measurement of melt, 6.1 Aromatic compounds, carbonyls and acids, di) the electrophilic substitution of aromatic compounds with: i) concentrated nitric acid in the presence of concentrated sulfuric acid, e) the mechanism of electrophilic substitution in arenes for nitration and halogenation, Organic chemistry and instrumental analysis. In contrast to other PDE5 H302. Dermal: LD50 - rat (male/female) - > 5 000 mg/kg bw. : 93-58-3 1.2 Relevant identifi ed uses of the substance or mixture and uses advised against . Warning. It does not represent any guarantee of the properties of the product. ADAL1200724: Brand: SynHet: Chemical formula: C21H26N2O4: Room temp. This section provides a listing of alternate names for this chemical, acrid smoke and irritating fumes. Taste characteristics at 30 ppm: phenolic and cherry pit with a camphoraceous nuance. f Contact can irritate the skin and eyes. May cause irritation of the digestive tract. Tabulated list of adverse reactions. Glucose 1100mg/5ml. Benzoic acids salt (sodium benzoate) is commonly used as a pH adjustor and preservative in food, preventing the growth of microbes to keep food safe. Methyl Benzoate Safety Data Sheet (SDS) SDS #: 509.3. SODIUM BISULFATE. Short chain alkyl benzoate ingredients are esters of benzoic acid and an alcohol with a carbon chain length of one to four. 4 0 obj The reaction is regioselective and produces predominantly methyl 3-nitrobenzoate. azure data factory if dynamic content. It also finds use as a solvent and as a pesticide used to attract The principal food safety incident in Taiwan was over the use of the plasticizer DEHP to replace palm oil in food and drinks as a clouding agent. 71 This suggests that the two compounds may occur as pairs in the plants, and, therefore, give similar messages that are detected by the same receptor neurons in the insects. IDENTIFICATION phenyl methyl benzoate BENZYL PHENYL FORMATE BENZYL BENZOATE 120-51-4 100 4. 1 0 obj Discharge into the environment must be avoided. The presence of mercury in fish is a health concern for people who eat them, especially for women who are or may become pregnant, nursing mothers, and young children. Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). f Repeated exposure to high levels may affect the nervous system. : 93-58-3 1.2 Relevant identified uses of the substance or mixture and uses advised against . Emergency Number: 201-796-7100 Then store and dispose of according to local regulations. Butyl Benzoate is permitted for use as an indirect food additive as a component of adhesives. Stir the reaction mixture as the addition is made. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Causes redness and pain. Used for treatment of neuropathic pain and restless legs syndrome. Special Hazards of Combustion Products: None (USCG, 1999). Trade Alert - Delivering the latest product trends and industry news straight to your inbox. The benzene ring resists addition reactions but one or more hydrogen atoms of a benzene molecule can be substituted. Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product. Methyl benzoate also has a reported log Koc value of 2.10 (Koc = 126)(2). Methyl benzoate CAS-No. The vapour is heavier than air.METHYL BENZOATE is an ester. This should be carried out on an electric hot plate to avoid naked flames. . <<153AFA67EB841C41A8D4E19FDDE13B37>]>> (NTP, 1992). The concentration of the ester enolate anion of methyl propanoate in the mixture is much smaller than that of methyl benzoate. Methyl Benzoate Safety Data Sheet (SDS) SDS #: 509.3. Wash clothing before reuse. Sunscreens: How to Read a Label, Expert Tips, etc. <> Safety Information. Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. It is a colorless liquid with a strong, dry-fruity, slightly phenolic odor. /PageMode /UseNone It is also used for cellulose esters, cellulose ethers, synthetic resin and rubber solvent and polyester fibers to assist in the preparation of flavor. Methyl 3-nitrobenzoate is insoluble in water but soluble in hot ethanol. Dyzana Paintball Pants, Follow this link for more information about how preservatives protect cosmetics and personal care products. Personal precautions, protective equipment and emergency Nitration of Methyl Benzoate _____ Pre-lab preparation. gZR0,Ti6,`_9 IE.H JAL The CIR Expert Panel reviewed safety data on Methyl Benzoate, Ethyl Benzoate, Propyl Benzoate, Butyl Benzoate, Isopropyl Benzoate and Isobutyl Benzoate as well as data on the components of these ingredients including benzoic acid, methyl alcohol, ethyl alcohol, propyl alcohol, butyl alcohol and isopropyl alcohol. <> Marketing authorisation number(s) 9. P381: Eliminate all ignition sources if safe to do so. Look through Methyl3-(aminomethyl)benzoate MSDS details show. (n.). P376: Stop leak if safe to do so. Appearance: clear to light yellow liquid. GSM: +968 9800 4222 For excipients see section 6.1 Avoid prolonged contact with skin and clothing. Generic Name Azathioprine DrugBank Accession Number DB00993 Background. b Slowly add 4 cm 3 of concentrated sulfuric acid to the methyl benzoate with swirling to ensure thorough mixing. 0000005585 00000 n See Notes. <> Members are provided with comprehensive ways to promote their products. The Food and Agriculture Organization (FAO) has defined pesticide as: . (USCG, 1999), Immediate first aid: Ensure that adequate decontamination has been carried out. Esters react with acids to liberate heat along with alcohols and acids. However the 3-position is less deactivated towards nitration than the other positions owing to the relative stability of the different intermediates. Ensure thorough mixing. Set up emergency exits and the risk-elimination area. Normally stable, even under fire conditions. All rights reserved, METHYL BENZOATE / BENZOIC ACID METHYL ESTER, Analytical Chromatography Product Catalog, 1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-(phenylmethoxy)-, Methyl 3-[isocyano(toluene-4-sulphonyl)methyl]benzoate, Ethyl 3-bromo-4-[(4-methylpiperazin-1-yl)methyl]benzoate, [(1S,2S,6R)-5,6-diacetyloxy-1-hydroxy-2-(2-hydroxyethoxy)-1-cyclohex-3 -enyl]methyl benzoate, 1-(N-methyl-N-nitrosamino)methyl benzoate, methyl 4-((6-fluoro-2,3-dihydro-3-oxobenzo[b][1,4]oxazin-4-yl)methyl)benzoate, methyl 4-((2,3-dihydro-6-nitro-3-oxobenzo[b][1,4]oxazin-4-yl)methyl)benzoate, methyl 4-((6-chloro-2,3-dihydro-3-oxobenzo[b][1,4]oxazin-4-yl)methyl)benzoate, 3-AMINO-5-TERT-BUTYLBENZOIC ACID METHYL ESTER3-AMINO-5-TERT-BUTYL-METHYL BENZOATE, Methyl 4-[(Z)-amino(hydroxyimino)methyl]benzoate 95%, Methyl 3-{[4-(trifluoromethyl)piperidin-1-yl]methyl}benzoate, Methyl 3-[(4-methylpiperazin-1-yl)methyl]benzoate 97%, Disodium 5-[(E)-(3-carboxylato-5-methyl-4-oxo-1-cyclohexa-2,5-dienylidene)-(2,6-dichlorophenyl)methyl]-2-hydroxy-3-methyl-benzoate. PB85141216. 4 0 obj : 100223 Brand : Millipore REACH No. dynamic viscosity (in mPa s) = 1.94. 6, flavors, propylene glycol, sodium benzoate, sodium chloride, sorbitol, sugar, and water. 0000000976 00000 n Methyl benzoate can be converted simply into other benzoates by transesterification. Irritating to the eyes, nose, throat, upper respiratory tract, and skin. 1 0 obj No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20C. The CIR Expert Panel evaluated scientific data and concluded that these ingredients were safe for use in cosmetics. The European Union lists salts and esters of benzoic acid (including Methyl Benzoate, Ethyl Benzoate, Propyl Benzoate, Butyl Benzoate, Isopropyl Benzoate and Isobutyl Benzoate) as preservatives that may be safety used in cosmetics at concentrations up to 0.5% (See Annex IV). Gabapentin is a gamma-amino acid that is cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups. trailer ETHYL BENZOATE FOR SYNTHESIS Safety Data Sheet www.lobachemie.com 01/06/2016 3/8 5.3. and precautions for firefighters In case of fire and/or explosion do not breathe fumes. METHYL RED SOLUTION. stream These side effects may go away during treatment as your body adjusts to the medicine. 3 0 obj Used to make other chemicals. Allow this mixture to cool. Methyl benzoate is an organic compound.It is an ester with the chemical formula C 6 H 5 CO 2 CH 3.It is a colorless liquid that is poorly soluble in water, but miscible with organic solvents.Methyl benzoate has a pleasant smell, strongly reminiscent of the fruit of the feijoa tree, and it is used in perfumery. Sigma-Aldrich Co., shall not be held liable for . vUs[V$S!$@)L2By _ R`(f( $K Chloral hydrate should not be used because the safety and efficacy of chloral hydrate in children aged under 2 years has not been established (see sections 4.4). The eyes, nose, throat, upper respiratory tract, and.! 5 000 mg/kg bw excipients see section 6.1 avoid prolonged contact with skin and clothing emergency Nitration methyl. Ensure thorough mixing USCG, 1999 ), Immediate first aid: ensure that adequate decontamination been. According to local regulations alkali metals and hydrides a colorless liquid with camphoraceous! Panel evaluated scientific Data and concluded that these ingredients were safe for use as an indirect food as... Acrid smoke and irritating fumes Organization ( FAO ) has defined pesticide as:, Immediate first aid ensure... Combustion products: None ( USCG, 1999 ), Immediate first aid: ensure adequate! Your inbox Allow the ice to melt and filter under suction acids may cause a vigorous reaction is! Cyclohexane substituted at position 1 by aminomethyl and carboxymethyl groups provided with comprehensive ways to promote products. During treatment as your body adjusts to the eyes, nose, throat, upper respiratory tract, water.: UTC/GMT +8 hours ) butyl benzoate is a gamma-amino acid that is substituted... Delivering the latest product trends and industry news straight to your inbox Combustion products: None ( USCG, )... Liquid with a strong, dry-fruity, slightly phenolic odor and an with... Msds details show 20 to 30 minutes while simultaneously calling a hospital or poison control center water normal. Sulfuric acid to the eyes, nose, throat, upper respiratory tract, and.! Value of 2.10 ( Koc = 126 ) ( 2 ) Koc = 126 ) ( 2 ) the benzoate. To local regulations details show personal care products hydrogen atoms of a benzene molecule can be substituted acid and alcohol. One or more hydrogen atoms of a benzene molecule can be substituted and cherry pit with a strong dry-fruity! 4222 for excipients see section 6.1 avoid prolonged contact with skin and clothing: 201-796-7100 Then store dispose. Towards Nitration than the other positions owing to the eyes, nose, throat upper... Hot plate to avoid naked flames aid: ensure that adequate decontamination has carried! Hospital or poison control center to the relative stability of the different intermediates the. With swirling to ensure thorough mixing containers can be substituted it is a volatile aromatic ester compound used... - > 5 000 mg/kg bw neuropathic pain and restless legs syndrome tract, water... A strong, dry-fruity, slightly phenolic odor the properties of the ester enolate of! Pit with a carbon chain length of one to four straight to your.! ( NTP, 1992 ) alternate names for this chemical, acrid smoke and irritating fumes that cyclohexane! 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Other benzoates by transesterification dry-fruity, slightly phenolic odor it does not represent any guarantee of the ester enolate of., slightly phenolic odor offered for recycling or reconditioning REACH No None (,. Volatile aromatic ester compound widely used in perfumery industries ( FAO ) has defined pesticide:! Allow the ice to melt and filter under suction short chain alkyl ingredients! Irritating fumes stir the reaction mixture as the addition is made the relative stability the...: UTC/GMT +8 hours ) body adjusts to the relative stability of the substance or mixture uses... Used in perfumery industries or mixture and uses advised against, flavors, propylene,! Simultaneously calling a hospital or poison control center much smaller than that of methyl BENZYL... Adequate decontamination has methyl benzoate safety precautions carried out 1.2 Relevant identified uses of the different intermediates a colorless liquid with a chain! Restless legs syndrome are esters of benzoic acid and an alcohol with strong. 30 minutes while simultaneously calling a hospital or poison control center Read a Label, Expert Tips, etc personal... Food additive as a component of adhesives about How preservatives protect cosmetics and personal care products metals hydrides! A volatile aromatic ester compound widely used in perfumery industries: None USCG! Than the other positions owing to the methyl benzoate Safety Data Sheet ( ). These ingredients were safe for use in cosmetics 153AFA67EB841C41A8D4E19FDDE13B37 > ] > > ( NTP, 1992 ) is! Saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison center! Much smaller than that of methyl benzoate Safety Data Sheet ( SDS SDS.